Bovilis swoosh, colored in green, pink, yellow Bovilis swoosh, colored in green, pink, yellow

Infectious Bovine
Rhinotracheitis (IBR)

A major cause of viral abortion in the world.
5-60% abortions in non vaccinated herds


IBR is caused by Bovine Herpes Virus-1 (BHV-1). This infectious respiratory disease of cattle makes cattle carriers once they are infected. Stress may reactivate IBR and the animal will start shedding the virus again, infecting other animals in the herd. Signs of IBR include fever and respiratory signs such as runny nose, discharge from the eyes and coughing. Infected animals can show a lower milk production and may experience abortion. Herds can be protected by vaccination and biosecurity measures to prevent introduction of the virus into the herd.

Clinical symptoms

Bovine herpesvirus 1 (BHV-1) is associated with several diseases in cattle:

IBR can directly impact ovarian structures, causing severe lesions on the corpus luteum. This makes developing follicles susceptible to degeneration. These follicles, if able to ovulate, have the potential to release oocytes of reduced viability.

  • Infectious bovine rhinotracheitis (IBR)
  • Infectious pustular vulvovaginitis (IPV)
  • Balanoposthitis
  • Conjunctivitis
  • Abortion
  • Encephalomyelitis
  • Mastitis

Treatment and prevention

Antimicrobial therapy is indicated to prevent or treat secondary bacterial pneumonia.

Immunization with modified-live or inactivated virus vaccines generally provides adequate protection
against clinical disease.

Biosecurity measures to reduce on-farm risk:

  • Diagnose and treat sick animals promptly
  • Isolate/remove sick animals from the group or herd
  • Keep different age groups and management groups separate
  • Reduce direct disease spread from animals
  • Take proactive risk reduction measures for farm visitors

Animal disease reduces global food production by 20% and costs farmers a significant proportion of their meat and dairy yield.

Bovilis® cattle vaccines against Infectious Bovine Rhinotracheitis (IBR)

Bovilis IBR Marker Live product packaging shoot

Bovilis® IBR Marker Live

A live Infectious Bovine Rhinotracheitis (IBR) vaccine for cattle, to reduce clinical signs and virus excretion associated with bovine herpesvirus type-1.

● LEARN MORE

Bovilis IBR marker inac product packaging shoot

Bovilis® IBR Marker inac

Bovilis® IBR Marker inac is an inactivated vaccine containing bovine herpesvirus type 1 to reduce clinical signs and viral shedding.

● LEARN MORE

FAQs: the big questions answered

Get the insights on vaccination of cattle.

● LEARN MORE

Go to your country website

Follow MSD Animal Health on social media